Quick answer: To unlock alchemy in Graveyard Keeper 2, follow the Plague Doctor story quest. When the Village Chief sends you to him, go back to your room and talk to Larry, the talking skull: a trap door opens to the dungeon under your house. The Plague Doctor gives you the Inquisitor's medallion and a door combination that open the Alchemy Lab tower north of your house. In the lab, study each ingredient at the Study Table (costs Science) to reveal its red, green and blue runes, then mix studied ingredients. The rune total decides what you get.
Spanish-speaking players search cómo desbloquear la alquimia ("how to unlock alchemy"), and the steps are the same. A common sticking point on Steam for how to unlock alchemy comes one step earlier: Larry won't show the trap door until the villagers' quests before it are done.
Quick facts
- Unlocked by: the Plague Doctor quest, through the trap door in your room
- Opens: the Alchemy Lab tower north of your house
- Costs to study an item: Science, sometimes Faith
- First recipe: Dream Dust = water + blood (1 green + 1 blue)
- Fuel: the lab burns firewood

How to unlock alchemy
Follow the quests to the Plague Doctor
Keep helping villagers until the Village Chief mentions summoning fairies and sends you to the Plague Doctor. Then talk to Larry in your room; the trap door leads down.
Clear the path to the Plague Doctor
Work your way through the dungeon to his room. He gives you the door combination for the tower.
Open the tower
Use the Inquisitor's medallion and the combination to open the Alchemy Lab.
Get Science
There's a Science Kit in the lab chest. Decompose it at the Study Table. Later, decompose blank paper or notes, or craft Science Kits at the Writing Desk.
Study ingredients, then combine
Studying reveals an item's runes for good. Put studied ingredients in flasks and mix. Any ingredients that add up to the right runes work, and a recipe you find is saved.
First recipes
| Recipe | Where | Runes / ingredients |
|---|---|---|
| Dream Dust | Laboratory I | water + blood (1 green + 1 blue) |
| Melted Fat | Distillation Cube | 1 Fat + 2 Clay Plates + 20 Fuel |
| Reanimation Liquid | Laboratory II | 2 red + 1 green + 4 blue |
Take the Dream Dust back to the Plague Doctor for two free zombies. Dream Dust, a Comet's Tail from the Astrologer and a tooth from a skull make the fairy summon.
Larry won't open the trap door? Players who were stuck here had skipped a villager step. One fixed it by talking to July again about the fairy.
FAQ
The Study Table could lock up after you inserted an item. Update 1.005 on September 24, 2026 fixed it, so update the game.
Through the Plague Doctor quest: Larry opens the trap door in your room, and the Plague Doctor gives you the combination for the Alchemy Lab tower.
Related
- Writing Desk: Science Kits for the Study Table
- Where is the Astrologer: Comet's Tail and Reanimation Liquid
- Energy: studying and crafting cost energy
- Map: where the tower is
Sources: a 7-tips guide, a 100-day playthrough and a recorded 100% playthrough on YouTube, Steam Community discussions, the 1.005 patch notes, GamesHorizon, gk2help.